We're Fixing What's Broken in Clinical Trials.
For decades, the industry has accepted a fundamental flaw: protocols are written once, but interpreted 87 different ways. We're changing that.
The Problem We Saw
Protocol Interpretation Shouldn't Be a Guessing Game
We've spent years in clinical operations—watching brilliant PIs struggle to recall complex criteria, coordinators second-guess eligibility decisions, and sponsors discover deviations months too late.
The pattern was unmistakable:
Sites receive 247-page protocols during packed SIVs
They juggle 12+ active studies simultaneously
Enrollment decisions happen under pressure, in real-time
Memory fades, but expectations remain perfect
The result? Screen failures. Deviations. Timeline delays. Data integrity erosion.
We realized the problem wasn't the people—it was the protocol delivery system.
Static PDFs weren't designed for real-time decision-making. Sites needed something fundamentally different.
Our Breakthrough
Protocol Intelligence: AI That Thinks Like a Medical Monitor
In 2023, we built the first Protocol Intelligence Platform—technology that transforms static protocol documents into real-time, AI-driven guidance.
Think of it as putting a medical monitor in every coordinator's pocket.
Our platform doesn't just store protocols. It understands them. It interprets eligibility criteria, answers complex questions in plain English, and delivers protocol-aligned guidance at the exact moment sites need it.
The impact was immediate:
Sites stopped guessing
Deviations dropped 40%
Enrollment accelerated
PIs stayed engaged
We didn't just build software. We created a new category.
Who we are
Clinical Operations Experts Who Got Tired of Watching Sites Struggle
Our founders come from the trenches of clinical research—CROs, pharmaceutical sponsors, and academic medical centers. We've lived the pain points we're solving.
Our team combines deep clinical operations expertise with AI engineering. We understand both the complexity of protocols and the pressure coordinators face when a patient is sitting in front of them.
Our mission is singular: Eliminate protocol interpretation variability across global clinical trials.
Our Approach
Built by Clinical Ops. For Clinical Ops. We don't build technology for technology's sake. Every feature in TrialPulse solves a real problem we've encountered in the field.
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We Start With the Protocol
Your 247-page protocol is the source of truth. Our AI ingests it, structures it, and makes it instantly queryable—preserving clinical precision while adding accessibility.
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We Speak Site Language
Coordinators don't ask "What is the mathematical definition of renal impairment per inclusion criterion 6?" They ask "Can I enroll a patient with eGFR of 58?" We answer the way a medical monitor would.
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We Integrate With Reality
TrialPulse works alongside your existing CTMS, EDC, and workflows. No rip-and-replace. Live in 72 hours, not 6 months.
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We Prove Results
30-day performance pilots. Real metrics. Measurable impact on screen failures, deviations, and PI engagement. We earn your trust through outcomes, not promises.
What Drives Us
Every Screen Failure Is a Missed Opportunity
When a site enrolls an ineligible patient, that's not just a protocol deviation—it's a patient who went through screening for nothing, and an eligible patient who didn't get the chance.
When timelines slip by months, that's not just operational inefficiency—it's delayed access to potentially life-saving therapies for thousands of people.
When PIs disengage because protocols feel overwhelming, that's not just an enrollment problem—it's the industry losing the expertise and passion of our best investigators.
We believe clinical trials can be better.
Not through longer training. Not through more monitoring. But through intelligent systems that support human decision-making at the point of care.
Our Commitment
Partnership Over Transactions
We don't just sell software licenses. We partner with CROs and sponsors to fundamentally improve how protocols are delivered to sites.
What that means:
Co-creation: Your feedback shapes our roadmap
Transparency: We show you exactly how our AI works
Accountability: 30-day performance guarantees on every pilot
Long-term thinking: We measure success in years, not quarters
We succeed when your sites succeed. When your timelines accelerate. When your data integrity improves. When your PIs stay engaged.
That's the relationship we build.
Where We’re Headed
Building the Protocol Intelligence Infrastructure for Global Trials
Today, TrialPulse serves leading pharmaceutical companies and CROs running complex, multi-site global studies.
Tomorrow, we're building:
Predictive protocol complexity analysis (before SIV, identify criteria most likely to cause confusion)
Real-time cross-site harmonization monitoring (detect interpretation drift before deviations occur)
AI-powered protocol optimization (help sponsors write protocols sites can actually execute)
Diversity-aware eligibility guidance (reduce unconscious bias in screening decisions)
Our vision: Every clinical trial, everywhere, operates from a single shared understanding of the protocol.
No more guessing. No more interpretation variability. No more preventable failures.
Just clarity. Confidence. Results.
Join Us
We're Always Looking for Clinical Operations Experts
If you've spent years in CRO operations, sponsor oversight, or site coordination—and you're frustrated by the same problems we are—we want to talk to you.
We're building a team of people who understand clinical trials from the inside and believe technology should serve sites, not burden them.
View Open Positions >>
Work With Us
See TrialPulse Working With Your Protocol
The best way to understand Protocol Intelligence is to see it answer questions from your actual protocol—in real-time, with your edge cases, your complex criteria, your amendments.
Here's how it works:
Share your protocol (we configure TrialPulse to your study)
Live demo (watch it answer your toughest eligibility questions)
30-day pilot (measure impact on one study)
No long-term commitment. No implementation nightmare. Just results.
Schedule Your Protocol Demo >>
Our Value
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Sites First
Every decision we make asks: "Does this make life easier for coordinators and PIs?" If not, we don't build it.
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Clinical Rigor
We're not a generic AI company. We understand clinical research. Our technology preserves protocol precision while adding accessibility.
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Radical Transparency
We show you how our AI works. We share our limitations. We admit when we don't know something. Trust is earned through honesty.
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Outcomes Over Features
We don't sell feature lists. We sell measurable improvements in screen failures, deviations, and timeline predictability.
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Global Equity
Protocol Intelligence shouldn't be available only to top-tier sites. Every site deserves the tools to succeed.
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Speed & Simplicity
Clinical trials are complex enough. Our technology should make things simpler, not more complicated.
By the Numbers: Our Impact
72 HRs
Average time to go live
(not months)
40%
Reduction in preventable
protocol deviations
5 SECs
Average response time
for complex eligibility
questions
24/7
Continuous access to
protocol intelligence
for every site
100%
Of pilots see measurable
improvement in
first 30 days
What People Say
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"The biggest operational risk in global trials isn't recruitment—it's ensuring 87 sites interpret your protocol identically. TrialPulse solved that."
— Senior Director, Clinical Operations, Top 10 Pharma
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"Our coordinators went from spending 20 minutes searching PDFs to getting answers in 5 seconds. That's not incremental improvement—that's transformation."
— VP Clinical Operations, Global CRO
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"We piloted TrialPulse on our most complex oncology study. Screen failure rate dropped 35% in the first 60 days. Now we're rolling it out portfolio-wide."
— Head of Clinical Development, Biotech